DSM Technology

We innovate and develop products that improve patients’ quality of life.

What is DSM Technology?

DSM stands for Degradable Starch Microspheres, a patented technology based on fully biodegradable, biocompatible particles derived from natural materials, designed to deliver innovative medical solutions.

DSM degrade to glucose in the human body

DSM are derived from potato starch

DSM are spherical particles on the microscale (1 – 1000 micrometers in diameter)

How DSM Works

DSM technology transforms starch-based microspheres into highly adaptable delivery systems that can be tailored to different medical challenges. By combining different formulations with various active ingredients, DSM can be used to address currently unmet medical needs, providing patients and healthcare professional with effective and innovative treatment options.

This flexible approach enables us to:

Whether used on their own or in combination with potent substances, DSM formulations create value for patients, providers, and the healthcare system.

DSM technology provides value for practitioners and patients

  • DSM are fully biodegradable, biocompatible starch microspheres developed to meet medical needs in several fields.
  • By adjusting production conditions, DSM properties can be modified.
  • This allows for the creation of different DSM formulations that are all combinable with a variety of different active ingredients and substances to generate novel DSM based products.
  • Use of DSM technology is supported by robust evidence.
  • While several DSM based products are registered and approved, research and development into new and innovative solutions to address currently unmet medical needs is ongoing.

DSM Product Categories

Because DSM are so adaptable, a range of formulations can be created, enabling diverse applications. Each DSM formulation is designed for different delivery methods and therapeutic effects:

Gel formulations have various medical applications, including:
• In the body as a surgical adjuvant or a post-operative treatment formulation with an active ingredient.
• As a topical gel in or on a wound.
• They have mucosal and transdermal delivery options.

Suspension-based formulation:
• Remain stable in a swollen state in suspension.
• Compressible for safe catheter or syringe delivery.
• Can be used on their own or combined with active ingredients, including highly potent drugs (e.g., chemotherapy agents).

Powder formulation for:
• Direct therapeutic effect (e.g. surgical hemostat).
• Inhalation and nasal delivery.
• Optional combination with active ingredients.

Solid formulation for:
• Dissolvable films, sponges, and freeze-dried forms.
• Potential to combine DSM and active substances across a range of therapeutic areas.

Clinical Evidence

At Magle PharmaCept, we are dedicated to advancing patient care through a strong evidence-based approach. Clinical research is at the core of our commitment to ensuring the safety and effectiveness of our products. With over 25 years of experience in product development and realization, we continue to invest in meaningful clinical data and outcomes research.

Our track record includes a large number of publications covering both preclinical and clinical studies, reflecting our focus on scientific integrity and innovation. This growing body of evidence supports the real-world value of our technologies and helps guide their responsible use in clinical practice.

DSM Products

Our DSM products are high-quality, clinically tested materials designed for use in a wide range of medical applications.

SmartPAN

SmartPAN® helps surgeons instantly detect pancreatic leakage during surgery, supporting secure closure and reducing complications.

EmboCept® S DSM 50 µm

EmboCept® S DSM 50 µm offers effective, temporary vessel occlusion for intra-arterial treatment of inoperable liver and lung tumors, used with cytostatic agents.

Advanced Wound Care

Our wound care products are developed to support the natural healing process by maintaining a moist wound environment and protecting against external contamination.